Endocrine Abstracts

Section 1: Case history: Persistent hyperinsulinemic hypoglycaemia may be caused by either a solitary tumour of the pancreas secreting excessive insulin, i.e. an insulinoma or, rarely by nesidioblastosis. A 70-year-old man was referred with symptoms of hypoglycemia. He had a positive 72-hour-fast with episodes of hypoglycemia and high insulin levels. Section 2: Investigations: EUS showed a small 3 x 4mm hyperechoic lesion in the body of the pancreas. His...

Background: Amiodarone induced thyrotoxicosis (AIT) is a potentially catastrophic situation for patients with cardiac disease who are at risk of life-threatening complications. We describe the protracted and challenging journey of a patient with Laminopathy and a significant cardiac history who developed AIT.Clinical Case: A 53-year-old man was referred with thyrotoxicosis (TSH <0.01mU/l, free T4 61 pmol/l, free T3 8.0 pmol/l) detected following comm...

Intro: Diabetic Ketoacidosis (DKA) is a medical emergency characterised by hyperglycemia, ketosis and acidosis. If left untreated it can lead to cerebral oedema, acute kidney injury, Adult Respiratory Distress Syndrome andeven death. Euglycaemic DKA (EuDKA) without hyperglycaemia is rare but increasing cases of EuDKAbeing reported in patients taking SGLT2 inhibitors.Case report: A 53 year old, Type 2 Diabetic was admitted for an elective cholecystecomy. ...

An anonymised online survey was created to evaluate junior doctor’s competency and confidence with decision-making scenarios in managing patients with diabetes at the end-of-life. 26 doctors working at the Beacon Hospital completed the online survey. A structured education programme was then delivered to the junior doctors where the critical information pertaining to the management of diabetes at the end-of-life was discussed, based on the ABCD 2011 and Diabetes UK 2013 a...

Background: Thyroid carcinoma consists of just 1% of all malignancies but is the commonest malignant endocrine tumour. Papillary thyroid carcinoma is the most common form of thyroid carcinoma consisting of 80% of all cases. There are very few case reports in the literature of papillary thyroid cancers presenting with distant to the pelvic organs. Distant metastases are noted in 1–3% of patients with thyroid cancer at initial diagnosis.Clinical case:...

Background: In Clinical Trials, Glucagon-like peptide-1 (GLP-1) receptor analogs liraglutide and semaglutide have been shown to cause weight loss, reduced systolic blood pressure, effectiveglycemic control with low rates of hypoglycemia, in patients with type 2 diabetes. Through a retrospective clinical study, the authors aimed to assess the clinical effectiveness of GLP-1 receptor agonists in the management of obesity in patients with Type 2 Diabetes.Me...